Peptides & Aesthetics Part 1

Overview

In Episode 3 of the podcast featuring Dr. William Seeds, the leading authority in cellular medicine, the discussion delves into the transformative potential of this field in redefining aging and enhancing overall health. Dr. Seeds shares his personal journey that led him from finance to medicine, highlighting the significance of cellular health in orthopedics and athletic performance, as well as the roles of exercise and nutrition. He emphasizes factors like oxidative stress and cellular signaling in aging, advocating for a focus on quality of life, personalized health approaches, and informed patient engagement. The episode also covers GLP1 medications, such as Ozempic, discussing their benefits for weight loss and cellular efficiency while cautioning against rapid weight loss and emphasizing the importance of healthcare providers being well-informed about these treatments.

Notes

Introduction to Cellular Medicine (00:00 - 08:10)

• Dr. William Seeds introduced as a global leader in cellular medicine
• Focus on aging, aesthetics, and the Ozempic revolution
• Dr. Seeds' personal story of losing his father at 16 sparked his interest in health and medicine
• Emphasis on cellular medicine's potential to redefine aging and enhance health

Cellular Medicine and Aging (08:10 - 17:44)

• Dr. Seeds' journey from finance to medicine, overcoming obstacles
• Importance of cellular medicine in orthopedics and treating athletes
• Cells as the focus for understanding and treating health issues
• Exercise and nutrition's impact on cellular health and adaptation

Cellular Approach to Health and Aging (17:45 - 27:57)

• Oxidative stress and cellular balance as key factors in aging
• Importance of maintaining cellular signaling for health
• Peptides as powerful tools for cellular communication
• Quality of life emphasized over longevity
• Criticism of focusing solely on biological age measurements

Personalized Approach to Health (27:58 - 37:58)

• Common reasons people seek cellular medicine treatments
• Importance of patient engagement and participation
• Constant adaptation and change in diet, exercise, and supplements
• Three to four-month rule for changing health routines

GLP1 Medications and Weight Loss (37:58 - 47:26)

• Discussion on Ozempic and other GLP1 medications
• Importance of slow, controlled weight loss
• Need for exercise to maintain muscle during weight loss
• Explanation of how GLP1s improve cellular efficiency

Advanced Peptide Treatments (47:26 - 57:39)

• Evolution of GLP1 medications: from Ozempic to Tirzepatide to Retatrutide
• Importance of proper use and understanding of these medications
• Discussion on potential risks of rapid weight loss
• Emphasis on the need for healthcare providers to have comprehensive information

00:00
Dr. Larry Fan
Welcome to the Fan Method, the aesthetics, health and wellness podcast dedicated to helping you look and feel your best inside and out. Have you ever wondered what the future of health, aging and beauty looks like? What if the key to reversing the effects of aging, transforming your body and achieving radiant health wasn't about quick fixes, but cutting edge science that works with your body at its most fundamental level, the cells. Today, we're diving into three of the hottest topics in health and beauty, aging, aesthetics, and the Ozempic revolution. Joining me is none other than Dr. William Seeds, a global leader in cellular medicine. As the founder of the Seeds Scientific Research and Performance Institute, Dr. Seeds has trained thousands of physicians worldwide on how to use cellular medicine and peptides to help patients look younger, recover faster, and live healthier, more vibrant lives. 

00:49
Dr. Larry Fan
In this episode, we'll explore how cellular medicine is redefining aging, how peptides are transforming non surgical aesthetics and enhancing surgical outcomes, and what's behind the ozempic makeover trend, plus how to overcome its challenges like muscle loss and sagging skin. We'll also share practical advice to help you take action safely and avoid common pitfalls in this new frontier of health. This episode is going to challenge everything you thought you knew about aging, beauty and transformation. Dr. Seeds, welcome to the show. It's an honor to have you here. 

01:22
Dr. William Seeds
Thank you, Dr. Fan. It's a pleasure to be here. 

01:25
Dr. Larry Fan
It's wonderful to have you. Now, I know you've been a pioneer in the cellular method space for several years, but let's go back to the beginning. You know, what sparked your interest in this field? 

01:36
Dr. William Seeds
Wow. Actually, it's kind of a personal story. It started back, I was 16 years of age and I had a very close relationship with my father, who was very athletic. My best friend, my mentor, we worked out together and he had a cardiac event on the track and he died in front of me and I could do nothing to help him. And it was something where it didn't make sense to me. Like, here was this person that I thought exemplified health and yet he dies. There's nothing I could do to help him. And I said right there, at that point in time in my life, I knew where it was headed. It was, it was, okay, there's gotta be answers, somebody, this can't happen to anybody else. 

02:46
Dr. William Seeds
And that started me on my personal journey of focusing on learning everything I could about and asking questions about why this happened. 

03:02
Dr. Larry Fan
Yeah. 

03:03
Dr. William Seeds
And it's gotten me here. 

03:06
Dr. Larry Fan
Wow. That's a really. That's a really powerful story. 

03:10
Dr. William Seeds
It still drives me Today, Yeah, it's. I'll never be satisfied. I'll never. The. You know, it's one of these things where you lose a parent early. I'm. I'm waiting for the day when my dad can tell me he's proud of me for what I've done, and that'll never happen. 

03:32
Dr. Larry Fan
Yeah, I can understand both as a parent and as a son. Now, I know that sounds obviously a very powerful sort of motivator for you. I wanted to ask you, was there a pivotal moment in your life when you realized the power of cellular medicine, whether it was a patient success story or a research breakthrough or another personal moment? 

03:58
Dr. William Seeds
Yeah, that's a. That's a great question. I think I was. So. So for me, I realized early on in medical school that there were things that we. That I. I had. How do I say this? So in. In college, I was a finance major, but I actually went to the library every day to do my own research on my mission, and that was to start figuring things out. I spent a lifetime while in school, while I was getting my finance major to focus on understanding the cell, understanding everything I could, asking my own questions. And I got to this point of where I'm about to graduate with this finance degree, and I end up, while I'm doing that, I'm like helping my friends with their biochem, their chem, their physics. And I'm like, I should do something with this. 

05:07
Dr. William Seeds
And that drove me to look at the potential of medical school. You know, back then when went, there were like, you had to follow this guided path, right, to get to med school. Well, I went to the people in charge to help you get ready for med school and so forth. And I don't know what you called them at that time, but they were advisors. 

05:33
Dr. Larry Fan
Pre med advisors. 

05:34
Dr. William Seeds
Yes, pre med advisor. And I walked in and I asked this guy, I said, hey, look, I'm about to graduate in finance. I'd like to. Could I take the test for medical school and go to medical school? This guy looks at me and he says, no. And he goes, you can't even do that. You're not in the right path. And I didn't know what that meant. And he really blew me off, and he pissed me off. And I said, I'm not going to use profanity here. But I just said, screw that. And I. I ended up. I ended up making an appointment down at the local medical school for someone to help me and. Cause I asked them, I said, look, I'm a finance major. I want to go to medical school. 

06:23
Dr. William Seeds
I'm pretty sure I could do okay and can you guys help me? So they were like. They had me down there. They said, now, look, basically you can't. You gotta do classes, you gotta do courses, you gotta. You know, we'll give you a plan, but it's gonna take you about a year and a half to. We want you to get your chem degree. So I said, you tell me what to do and I'll do it. And so in a year and a half, I got my chem degree. And then I did that. That thing you could do back then. I applied early admission to the same place because they were nice to me. And. And I got an early admission. And I was the only one from our school at that time that got the early admission. 

07:06
Dr. William Seeds
So I went back to that advisor and I said, hey, I heard you got somebody into this medical school. And this guy said, yeah, he's one of our good students. And it was just. It's. We're just so excited for him. And I go, that was me. I go, do you remember me? And this guy's like, looking at me. I go, you're the guy who told me I couldn't do this. And so that's what. You know, it's always been those challenges that pushed me. I don't know if that answered the question. 

07:35
Dr. Larry Fan
Absolutely, absolutely. 

07:36
Dr. William Seeds
But it was that beginning that led me to. There's always answer. Don't let anybody tell you can't do anything, because you can. Right? 

07:46
Dr. Larry Fan
Yeah. 

07:47
Dr. William Seeds
And so that took me into the field of, you know, I saw. I saw things a little different in medical school. It was hard to stay engaged because I just had so many other things in my head. And, yeah, I got through that and went into orthopedics because it was a place I saw where cellular medicine could be applied very early, you know, because of the. The injuries, the fixes that could occur quickly. And. And so right off the bat, I started seeing how if you look for not just fixing something surgically, but if you set your patient up to set the environment right in the body, surgery is going to be way better. Right. And then I. And serendipitously, I found that I was seeing people not even get into the or because I was making them better that I wasn't really expecting. 

08:43
Dr. William Seeds
And then that just took me deeper and deeper, and so I was in a good place. Fortunately, to. At that time when athletes had. The business has changed a lot in professional athletes, but back then, decisions could be made quickly. There Weren't too many people that had control of the athlete. And you could really do a lot to get these athletes that potentially were going to lose their big contracts because they were told they were done. So I ended up being that guy that kind of was under the radar who I helped some people get there. And so that kind of started the. 

09:25
Dr. Larry Fan
Yeah, yeah. 

09:26
Dr. William Seeds
So it wasn't just one, it was just, it was a, you know, repetitive. I was just fortunate to be in the right space with the right type of patients, you know, that wanted to be engaged and who were as, you know, with your surgeries and the things you do with your patients. It's a team effort. Right. And I mean, just like you're doing here and educating your patients, I mean, who does that? This is amazing what you're doing, by the way. And that was the part that made it easy because these people had big incentives to get back. Right. So I had total control from the beginning. 

10:08
Dr. Larry Fan
Yeah. 

10:08
Dr. William Seeds
To the surgery, to the treatments, to therapy. And I was fortunate enough to also be in a facility that I could get them back on their playing field and, you know, do all the things that worked. 

10:23
Dr. Larry Fan
So that's, it's fascinating to hear sort of your early interest and how that's translated into the rest of your career. But one of the interesting things to me, most people, you know, go to medical school, they probably start off thinking about, you know, the person. Much like, you know, your, you know, father is obviously, you know, an inspiration. And yet people think of, you know, whole, whole, whole person's body parts, organs, you know. But it sounds like you are from an early stage already thinking about the cell. How did you know, have the insight to, you know, to realize that the cell was the place to focus? 

11:05
Dr. William Seeds
That's a great question that I think I can expand on significantly. So you'll have to shut me down because I could go on for days. But it all, I'm going to tell you, it started with, again with my father in training and working out and respecting the body. He taught me something that I'll never let go of. It's what you put in, not just your brain and learning, it's what you put in your body and how you treat your body is how it's going to respond. And so I learned very early on with working out training, resistance exercise, and we didn't know it, but high intensity training that I didn't know I was doing back then, that's now a name that you could, I would see changes in myself that I wasn't seeing in other people at my age. 

12:07
Dr. William Seeds
And I was doing more, I was capable of, I was comfortable and I could work out and you could start to see I could feel how I would recover better. And, and so when you see, you know, as a young person, when you see doing like resistance exercises and you see a muscle get bigger, it just made me think about, well, why is that? Ha. You know, I know it's working. So that was always in my head. And then when I got into the aspect of trying to figure out how my father died as a healthy person, my direction was very clear. It had to do with how things change in the body. And there had to be a beginning. And so I'm not going to say it happened overnight, it just happened over. 

13:04
Dr. William Seeds
I was very fortunate to have a book that was written by some biochemists that I read 33 times in college. It was like my bible that actually had a chapter to teach you how to research. And so I learned how to do things. Didn't have the Internet then, but I could, you know, it was that constantly asking questions and it got me to that place of, okay, well, if I'm comfortable in this exercise world, there's gotta be a lot of literature out there that starts talking about exercise. And so as you got into exercise and nutrition, there was this vast, you know, vault of papers that have been written for the last 40 years. You know, it's just, it's never ending. That would start getting me to these places of, you know, you read something and you don't understand it. Right. 

14:01
Dr. William Seeds
And so then you got to read it again and then it leads you to another place. Because you keep asking questions. 

14:07
Dr. Larry Fan
Yeah. 

14:07
Dr. William Seeds
And that got me to, oh my gosh. This cell is this place of incredible intelligence that we don't understand. And no one has the answer to how this cell adapts, right. To exercise, adapts to life, adapts to everyday stressors. And it was just fascinating and it just kept me engaged. Okay, I got to learn more about the cell. And then when you start finding out what's in the cell, oh my gosh. It's just, I'm still learning, right? I, I, I, I know this much. It, it's just. So that's kind of a, it's a never ending passion to learn more. Because the more you find, the more you search, the more you realize you don't know enough. 

14:56
Dr. Larry Fan
Yeah, absolutely. I can totally relate you know, as a fellow surgeon, you know, I always joke with some of my patients about anatomy. You know, the human body, an design like organism. Right. Anatomy probably hasn't changed in forever, and yet the more you learn about anatomy, the more you realize there's another 10 layers to understand it. Right? Correct. It's fascinating. Even we can slice open any part of our body and start unraveling the layers, but there's always another layer to sort of see and to know about. And they actually have real applicability in surgery, particularly as well as medicine. 

15:35
Dr. William Seeds
Yeah. And we used to. It just. I'm sure it's the same, you know, it's the. From the same viewpoint. I used to. I used to think of anatomy as destiny, you know, if you know your anatomy, you're going to find a way to get there. Right. But it's always, it's. It's so funny. It's. You see, you know, you see it in your textbooks, right? You think you know it all and you get in there and it's like, okay, I gotta figure this out. This isn't like the book and that keeps humbling you all the way through, right? 

16:09
Dr. Larry Fan
Yeah, yeah, absolutely. 

16:10
Dr. William Seeds
And anatomy is destiny, but you gotta figure your way around because the population is heterogeneous. You know, there's all these variants in everybody and. Yeah, so I totally agree with you. 

16:23
Dr. Larry Fan
Yeah, I know, it's fascinating. 

16:25
Dr. William Seeds
Right? 

16:25
Dr. Larry Fan
Biology itself. Fascinating. And I wanna transition to talk a little bit about aging. So this is a topic of interest certainly to sort of our viewers, but also really to the general public. But you know, with aging, a lot of us, you know, think of the external signs of aging, like wrinkles and gray hair, but it's what happens inside that really matters. Right. And the cell is fundamental to aging, is that right? 

16:53
Dr. William Seeds
Absolutely. So the. So by going back and talking about what I said before, about understanding just how a cell is normal in normal conditions, how a cell reacts to and adapts to exercise, how a cell reacts and adapts to certain stressors, if we know the way the cell thinks. Because it's always the same path. Molecular pathways don't change. You know, molecular pathways are kind of like the destiny, you know, anatomy is destiny. Molecular pathways are the destiny of the cell. And so once you start appreciating, like, how the cell talks and communicates in signals, you start. And the research and data that's out there that's already shown us how a cell reacts normally to, you know, to exercise, to reduce sleep, to different nutritional statuses, to stressors. Anxiety, viral infections, bacterial infections. You know it. 

18:10
Dr. William Seeds
Once you know how the cell tries to adapt and adjust, you start seeing pathways. That's what happens. That's how I see things. And, and then you start to appreciate this incredible intelligent being that is a cell that, if you see that, then. And you know the cell is, can make, it's meant to make its own decisions to survive and adapt. Then you start to appreciate that having the knowledge base of what a normal cell does, and then let's go to the other side and say, what happens to that cell when it becomes cancerous? Well, then you learn a whole new aspect of how cancer actually can rearrange all those pathways in favor of itself to immortalize it and separate itself from other cells and live as long as it wants to live, because it's pretty smart. 

19:12
Dr. William Seeds
Well, so if you start seeing all those things, then it only makes sense to start going back and looking at all the literature with aging and all the literature, and there's a plethora of information out there in, you know, starting with animal studies and, or worms, animal studies, humans. And then we start to see, okay, this is what happens during aging. We lose certain signaling agents over time. Why do we lose them? How does that happen? Is it different under different circumstances? And the answer is yes, yes. So then you come to respect this fact that, okay, maybe we can do some things to influence the cell to, let's say, age gracefully, to give it more capability of handling things, because that's what basically happens, that aging is more or less. 

20:14
Dr. William Seeds
The cell just doesn't have the capability to do what it wants to do because it's not getting the signaling. And so if we can do things to enhance the signaling, hence good diet, great exercise, good sleep, reduced stress, just. Just the right things, those things have a great influence on how that cell ages. And so if you can put all those things together, it's amazing how you can look to not now treating a symptom, right? You can go to the beginning and say, hey, I've got a root cause that I know this patient. After the age of, you know, at this age from 30 to 50, we start losing mitochondria, we start decreasing the amount of NAD production, we start losing certain important amino acids in the Krebs cycle. All these things just start to make sense. 

21:20
Dr. William Seeds
And so if you know that well, why don't you work backwards and let's start making the environment better? Is that, Is that. 

21:29
Dr. Larry Fan
Absolutely. And if you were, you know, and if we wanted to sort of Explain this in simple terms to the person who's curious, well, what exactly, you know, is happening to this cell? Or why does it, you know, why is it not getting the signaling? What does that lead to? If you had to describe it in simple terms, you know, maybe I'll ask, is it, is that the heart of it? Is it, is it about sort of oxidative stress? And I know, you know, one of your, you know, excellent books, you know, the Redox was about, you know, about that in particular. 

21:59
Dr. William Seeds
Yeah, and that's exactly. It's a balance. The cell's losing a balance. So a cell has to adapt every day to life and it goes through all these biochemical pathways to adapt to everyday life. Well, sometimes a cell has to work hard depending on what the stressor is to manage that day. So those stressors can cause the cell to work harder, causing a stress, and we call it an oxidative stress. The cell is also capable of making its own antioxidants that can control those stressors, which we call reactive oxygen species. So, so it's a balance. And so what happens is the cell loses the capability of maintaining balance. And that's where everybody, I think, goes. I think that's what people don't respect. It's just a balance. It's not supercharging something. It's keeping the physiology and the biochemistry of the cell in balance. 

23:08
Dr. William Seeds
And that's all the cell wants. It's just like, give me a little bit and I'll show you the way. And that's, I think you hit it on the head with what you said there. 

23:18
Dr. Larry Fan
Yeah. And it's something that I, you know, have come to really appreciate so much in biology, medicine, nature. It is about balance, you know, sort of what I call like a yin and yang. Right. You know, is it inflammation or is it healing? Is it fibrosis? You know, and all of these things. And the amazing part, Mother Nature, naturally, when we're young and healthy, you know, gets these things often quite right. But then as we get older, the environment changes and, you know, and things get out of balance. And we see that with so many things. You know, I want to sort of ask you, and so how does, how can cellular medicine, how can it sort of, how does it play a role in helping to sort of modulate aging, so to speak, or to improve aging? 

24:04
Dr. William Seeds
So that's the next step, right? That's the cellular medicine allows the physician or the healthcare provider to have a maybe just a little better look Inside of how they can just help the cell become healthier. Right. It's all that. All it is give the cells the signaling it needs to be healthier. And it's that simple. It's giving it. We're not trying to change. We're not trying to tell the cell what to do. We're trying to give its signaling. It's, it's messaging because cells are talking. They're always talking and communicating. And so as you aged, communication goes. Gets a little off the track and by using cellular medicine, and cellular medicine is all about keeping the balance. And you do that through a very, it's a very comprehensive look. It's not. There's not just one answer. 

25:07
Dr. William Seeds
It's not one pill, it's not one supplement, it's not one exercise. It's the combination of everything in giving the cell its multiple ways of retaining its balance. So you can use peptides and supplements and repurposed drugs and good diet and good sleep, and all these things come into play. And it, and it just keeps going. I mean, you can get into all of the, you can get into the circadian rhythms of the cells and the central pacemaker and the hypothalamus. You can, I mean, you can just go and go. But if you have that knowledge, it's just, it's incredible. If you can give that cell the right signaling agents can really make a difference. 

26:01
Dr. Larry Fan
Yeah, absolutely. And so, you know, in practical terms, for the average person, we're talking about a number of essential elements. So nutrition, exercise, rest, stress management. And then on top of that, the extra things are. Are they peptides and supplements? Are the. Is it, you know, more than that? Is it. 

26:24
Dr. William Seeds
So I, so that's a great question. And, and I think from the cell signaling aspect, the peptides are the more powerful agents there because they're actually, they're actually what the body makes, depending on the signaling and what cell makes them. It's, it's how cells communicate. It's how they maintain their balance. So all we're basically doing is we're synthesizing something that you make to help that cell do a better job at whatever you're trying to work on. If it, you know, for everybody, as things, as time changes, it's. It's what, it's brain fog, it's anxiety, it's performance, it's. How do you help the cell do a better job with all of those? Well, there are ways that you can use these signaling agents that we make and I think the best. Gosh, if we had to look at this right now, we could name. 

27:27
Dr. William Seeds
We could say two things. We could say, everybody know what insulin is? Well, that's been around for over a hundred years and changed the landscape for people to survive. Diabetes. Guess what? That's a peptide. When I first started lecturing and I'd say, how many doctors out there use peptides? Nobody raised their hand. I go, does anybody use insulin? Everybody raises their hand. It's that understanding what these are and what's the second wave since insulin. It's this. It's this explosion of GLP1s of the WeGovies, the semiglutides. It's another explosion of. And again, that's a peptide. That's something you make in your L cells in your ileum and proximal colon. You make those. So it's. It's just fascinating where this is all going finally. Where. It's not that we haven't known about it. I mean, we've known about these agents for the last hundred years. 

28:32
Dr. William Seeds
It's just now we have the ability to synthesize and utilize these. Now in a place if you're familiar with these pathways, you can really make some changes. And so I think that's where, why everything's exploding in this, this area. And, and, you know, the aspects of having to. All of us having to go through Covid, where people all of a sudden now are paying more attention to their health, like, what could I do to offset another potential process like what's happened with COVID So that's kind of, I think, why this has all become more relevant. 

29:14
Dr. Larry Fan
Yeah, it is fascinating that Covid definitely has introduced a new stress into all of our lives, in our health. And, you know, when you see people, you know, having these very profound and extreme reactions to, you know, a virus, it definitely has, you know, woken a lot of people up to just look more closely and to really pay attention. 

29:34
Dr. William Seeds
Absolutely. 

29:34
Dr. Larry Fan
Silver lining now when it comes to sort of, know, developing a treatment program, you know, for patients. You know, on the one hand, there's. There's sort of biological age and how, you know, a person's body or cells function. There's chronological age, obviously the actual age that they are. But how do you actually, you know, does biological age? Is that something that plays into a role in how you assess people and design treatment plans for them? And if it is, how do you actually assess that? 

30:06
Dr. William Seeds
Well, and that's where. That's a really good question, because I don't want To sound, you know, I'm pretty black and white about things sometimes, about what's out there and what people are promoting. And I think if I could get people to focus on, you know, what is biological age, chronological age, what does that really mean? To me, it means nothing. It's about if my focus is on the cell to improve the efficiencies and flexibility, meaning making that cell healthier. Right. Well, I'm going to be taking care of all those problems. So age, that stuff doesn't matter. And what are you going to treat when people get a methylation study and say, oh, my biological age is this, but my chronological age is that? I'd say, what the hell does that mean? You know, what are you going to. Does that mean anything? 

31:03
Dr. William Seeds
It means nothing. It's a, to me, that's a. People have fallen into the marketing of things that don't matter because if you're focusing on the cell, you're never going to go wrong and you're going to be accomplishing all the things that you want to accomplish in improving this age issue. But it's like, but let me take that a step further, Dr. Fint. If you're, that's almost like you're focused on, and no disrespect to anybody focusing on longevity, but it's all about tomorrow and the next day. It's quality of life. Right. It's not. You can, I could show you hundreds of thousands of people that live long, but they're not healthy and they're miserable. What does that mean? Means nothing. 

32:10
Dr. William Seeds
If you're focused on the cell and you're focused on quality of life, then maybe in the next 50 to 100 years, we'll see from the research that, oh, we are improving longevity. Right. So that's kind of how I. 

32:26
Dr. Larry Fan
It is. It is more health span as opposed to. 

32:29
Dr. William Seeds
Absolutely. 

32:30
Dr. Larry Fan
Lifespan. 

32:31
Dr. William Seeds
You hit it on the head. 

32:32
Dr. Larry Fan
Now, of course, everyone watching there, most people will be wondering, well, gosh, so, you know, you're telling me you can, I can get some treatment and have my cells and my body sort of function better so I can have, you know, more energy, you know, better quality of life. But people will wonder like, hey, what is, you know, realistic? If I'm 70 years old, can I feel like I'm 20 again? You know, is that realistic or is that even like the wrong way to be thinking about things? It really is about, you know, it's really about just being the best sort of version of you. And as you know, better tomorrow, you know, today and tomorrow. 

33:12
Dr. William Seeds
Boy, you asked really good questions that, so that's where the patient and doctor or healthcare provider, the interface becomes so important because you have to have participation. I think anything's possible. I don't ever discount anything. Anything is possible. So if you take that 70 year old, for example, is it possible for them to feel like they felt when they were in their 20s? Absolutely. But it's going to take hard work. It's not going to be an overnight thing. It's got to be a process that the patient buys into first. They've got to feel and see some results. And then what they have to do is they have to be part of the equation and start asking questions too. Hey, I like the way we started here. What else can I do? 

34:09
Dr. William Seeds
And this is where we become, I think, even more powerful when we empower our patients with information. And not all the, how do I say this? Not all the noise on social media and stuff, it's like, hey, let's focus on real research, real science. Let's use this to your advantage. And you can be just as smart as I am. I, I just spent longer doing this, longer time. Right. And so then you empower your patients with information where then they're better at their job in reaching these goals because it just doesn't, you know, you can't throw all this stuff at somebody at once. It's, you give them some ways to improve their quality of life and then that may open the door for, hey, what if you changed your diet? Hey, what if you exercise? Hey, what if you slept better? 

35:04
Dr. William Seeds
Hey, then oh my gosh, it's, it's always, I'm always learning right from my patients that it's fascinating to see where that goes and humbling. 

35:20
Dr. Larry Fan
Out of curiosity, have you always taken that approach with helping empower patients to start sort of with, you know, sort of almost like one thing or one win and then sort of get the opportunity? Or were you like if you were like most of us surgeons or doctors tend to be like, no, I see the whole picture and I want you to do everything because I know that's what's going to get you the best thing. But I'm, you know, I'm curious, is that something that you've evolved to? 

35:46
Dr. William Seeds
So I would have been really smart if I would have done it like I just said, and you hit it on the head. I knew what I could do for people and I made the Mistakes of throwing everything at once. And I learned very quickly that doesn't work. And it didn't make sense either. It was probably more enthusiasm and just excited that I wanted to help people and I knew how to do it. And I was humbled so quickly in finding out that, hey, you gotta build foundations and you gotta take steps and not everybody's gonna go where you want them to go. So you gotta, it's an art, right? And, and it's. And you gotta continue to respect that. And so I'd like to say I was really smart and yeah, that's what I thought. But no, I made all the mistakes. 

36:40
Dr. Larry Fan
Right, but you were smart enough to realize it. You had a lot of people that, you know, continue to just to bang their head against the wall trying to, you know, ask patients to do things that maybe is too much. 

36:51
Dr. William Seeds
So I, I would. You can't say enough about how smart your patients make you. And they can never ask a bad question. They can ask it in different ways that you never thought of things before. But yeah, it's a true. You're. You just gotta, you gotta figure out where that person is gonna be comfortable. And I think you always are gonna win. When you start out more minimalistic and get. And let them experience some changes in certain ways of whatever you're working on, there's definite ways to go about working on metabolism or the immune system or the microbiome or things to get changes quickly and then get them engaged and then just working through steps. 

37:46
Dr. Larry Fan
And on that note, to make this very concrete, what are the most common reasons that people will actually come to you to sort of start a treatment program, whether it be peptides or something else. But what are the most common health issues or symptoms or complaints that people will come in to see you for? 

38:07
Dr. William Seeds
Well, it's very broad based. It's that older person who feels that they've lost those golden years and they just want a little bit more out of their life to be able to just improve the quality. It's always quality of life, by the way. Everything's quality of life. It's not. I never have anybody come into me. I never have anybody come to me and say, I want to live longer. It's like, how can you make tomorrow better for me? Right? And so you see patients that are. That think they're healthy, right. And that are just looking to do better in the gym or better performance in the boardroom or do a better job when it comes to immunity because of their, you Know, more colds or things like that. 

39:04
Dr. William Seeds
Or, or you get the complicated things of real immune diseases or genetic diseases or that's where it's expanded because I tend to see things that. Where people have seen a lot of people, and I'm like, I, I'm not the last resort because they're. There are many people as smart as I am, or I shouldn't say smart, have the experience. But I tend to see these people that are desperate because they haven't gotten any answers or they haven't gotten there. And that's where I really learned the power of just take it slow and show them they're capable, giving them the confidence. Right. So I see all kinds of issues that people come for. So for instance, I'll even have people that'll come to me and say, Dr. Sees I'm looking to lose weight, and I'll be like, okay, so let's dive into that. 

40:11
Dr. William Seeds
And what I tried to explain to people is like, okay, what if I kind of reworded this for you and said, what if I told you, like, if we go down this road of these ozempics and we'll go these GLP1s, if we're looking at the potential of using something like that. What if I told you weight loss is a side effect? It's. What is this peptide going to do for the cell. And cell efficiency and cellular resilience? And like, what if I told you that was my play here and what I want to do and the weight loss will happen, but we have to do it right. And I think that's where a big disconnect has been also, unfortunately, and keeps you guys probably really busy, too. Yeah. 

41:04
Dr. Larry Fan
I don't know if it's obvious to viewers, but, you know, sitting here next to you know, I can tell you're a shining example of living with great vitality, you know, above the age of 50 and, you know, you have incredible amounts of energy. You have clearly a very robust physique and a lot of passion for life. And, you know, I'm curious if you know, can share sort of, you know, what are some of the things that, you know, that you do for yourself to sort of. For you to be able to live every year sort of better than the last. 

41:42
Dr. William Seeds
Sure. 

41:42
Dr. Larry Fan
And then also why it's important to you. 

41:45
Dr. William Seeds
Sure, sure. Well, let me start out by saying I still make all the mistakes everybody makes in sometimes pushing myself too hard. And that's something I don't know if I'll ever be able to get past that. But I'm fortunate to have spent all this time to build my knowledge base, to actually be an example to my patients, to show them that the age is not a discriminator. I'm 63, and every year I am stronger, faster, smarter. I feel more alive. I feel more like there's more I want to take on. And I think it's because it didn't have. I've worked very hard at it. It's a discipline. It's a lifestyle that is. That's constantly changing. So people say, Dr. Sees, what diet do you follow? Well, I keep changing my diet. I keep adjusting it. I'll go Mediterranean, Carnivore, Paleo, Mexa, keto, and Carnivore. 

43:06
Dr. William Seeds
I mean, you have to respect. And I think this is the best way to give an example of. If you lift a weight and you lift it many times, the cell changes. It hypertrophies, it gets stronger, but then it plateaus. And no matter how much you keep working at that same exercise, it doesn't change. But if I change the type of exercise in a different way to stimulate that muscle, I then change it again. And that's because the cell is. Remember, this thing's intelligent. It's adapted. It's adapted to the environment I've set for it because it's smarter than I am. So it's like, okay, met these goals. You can do it as much as you want. You're just, you gotta give me something more. So it's no different than all of the things that I do with or that I've come to respect. 

44:02
Dr. William Seeds
Like, there is no one diet. There is not one fasting program. There is not one exercise program. There is not one. There's not one supplement. You take forever, which is wrong. It's changing. It's constantly changing because your cells are adapting. 

44:26
Dr. Larry Fan
And how often do you think things need to be changed up? And I imagine it may be different for different types of, you know, cells or functions. But generally speaking. 

44:35
Dr. William Seeds
So I, you know, that's a great question. And that's. If you're working with a patient, you kind of learned that they're the patients that haven't been in this world and they're just starting. They adapt really quick, or, I mean, they can get some big changes really quick and keep moving for quite a while, and then they reach a plateau. And that could go for six months or a year, just depending on what you're working on. And then you get the people that are more fit and more resilient. To adaption are more resilient. And those are the people that are kind of where you do have to, you kind of have to change it up. If you had to pick a number. 

45:22
Dr. William Seeds
I kind of have this three month rule, three or four month rule where you gotta just change at that period of time it's become. I can't. I'm sure we'll validate this in some way in years to come as we, as AI helps us sift through, you know, genomics, transcriptomics, proteomics, metabolomics. It'll help us make those decisions much better. But I kind of use that and that's what I've done. That's how I kind of manage my life. And okay, it's three, four months. Things are getting stale. What are we going to do next? Well, how am I going to, what am I going to work on? Is that it's a. And every time I think I have it right and I think, oh my gosh, I'm training better. And then I, because my life does focus around exercise. 

46:17
Dr. William Seeds
I mean, I think I can't say it enough. Exercise and nutrition and sleep and stress. I mean I have all these other great tools and I think they're awesome and it's what balances this whole process. And, and you know, you can make up things that you lose with aging, but it's a whole big picture. 

46:34
Dr. Larry Fan
Yeah, yeah, absolutely. It makes a lot of sense now, you know, for people who are watching and they may be interested in thinking, gosh, is this for me? Is there, is there anybody who is not a candidate to, you know, to have treatment? 

46:49
Dr. William Seeds
Absolutely. It's so they're. The people not to have treatment are the people that aren't engaged that come to you and say, do your stuff to me and I'll do it and I don't want to know anything more. That's not the right person. They have to be engaged, they have to be asking questions or it's never going to work. I made those mistakes early. Where you'd have, I mean, perfect example would be the long time ago when the athlete would come with their agent and their agent would do all the talking. But the patient wasn't talking to me. 

47:24
Dr. Larry Fan
He wouldn't be there. 

47:25
Dr. William Seeds
And you're like, well, what do you think? Whatever he says, you know, and I'd be like, can't help you. 

47:32
Dr. Larry Fan
Do you think that's because it's, you know, a lot of people want sort of the silver bullet, but and that's what they think a peptide might be. 

47:39
Dr. William Seeds
But 100% you. You can't. You couldn't. You know what. What makes a peptide or a supplement or a repurposed drug really work? Well, it's when you engage exercise and nutrition and sleep, it takes it to a whole nother level. I mean, you can do things to help people kind of get on that track. That's what I said. That's what I said. How these can be powerful tools to get the patient engaged. And I have to say, one of the most powerful tools I've seen today now are these GLP1s. And what's interesting is I've been teaching and utilizing GLP1s for over 10 years. I mean, we started in this area of talking about how GLP1s and the research was there, it's always been there in cell efficiency and what it does to improve metabolism. 

48:43
Dr. William Seeds
And the game changer was that was something that had to be done every day and twice a day, like an injection. Well, that wasn't an easy thing to do with people then. But for the people that were utilizing them to help sell efficiency, it was a game changer. But until 2017, about. I think that's when the first ad for Ozempic came out and they used that music to. Oh, oh, it's Ozempic. You know, it was like they stole this great song magic, and they put Ozempic in it. And I was. You can't get that out of your head. It was brilliant. And it was the first time they'd ever advertised directly to people. Right. Well, it was once a week. Game changer, compliance. People started thinking about it, Ned, you know, and. And so that was. 

49:43
Dr. William Seeds
That was a pivotal moment of where all of a sudden I had a better tool because of compliance. And so I could use one tool and get the patient engaged where. Oh, my gosh. You were. You were right. Yeah, I lost this weight, but, boy, I feel better. I'm. My. My brain fog is gone. My anxiety is better. My. I feel more energized. My workouts and recovery is better. And of course, a lot of other things went into the, you know, to working with the GOP 1s at the time. But you captured the patient and then it just went from there. Right. And so I hope that gives you some. 

50:28
Dr. Larry Fan
Yeah, absolutely. So speaking of Ozempic, you know, a trending term in sort of in our. In the aesthetic industry is the notion of an Ozempic makeover. So, you know, using ozempic, really obviously you know, losing weight, but with the losing weight, a physical transformation happening, you know, that often combined with other aesthetic treatments, whether they be, you know, non surgical or surgical. But I wanted to ask for your opinion. Do you think that is, you know, sort of a sensible concept or do you think it's, there's something misguided in it or. 

51:06
Dr. William Seeds
I think it's a complicated answer, but I think it's, I think it goes back to understanding what your objectives are and what people losing weight, whether it's through Ozempic or any other matter of if you're going to lose weight fast, things aren't going to go great. That, that's just, you're gonna, you're headed in the wrong direction. It's about doing it slowly and at the same time, you know, when you're losing weight, when the cell's getting more efficient in how it utilizes its nutrients, it changes, the metabolism changes. And, and so it's really like with Ozempic or for instance, it's, it's trying to let the body, the cells utilize its own fat basically to improve its efficiency. And so that's something that you have to respect and understand that it's not something you want to accomplish in two or three months. 

52:20
Dr. William Seeds
It's something that can take a good year and a half to do appropriately over time so that you don't, so that you can, the rest of the body can catch up with potentially what's happening with that weight loss because people don't realize this when they're overweight. There are, that's a true inflammatory state of the body and the fat is different, the immune system's different. And so a lot of things are changing when you're using something like that and you have to respect that and you have to have other things happening. Also. You've got to stimulate, you got to get people into an exercise program to work on muscle, for instance, because I don't care what weight loss program you go through, you're going to lose muscle. But what you don't, what people don't understand is the muscle they're losing if they're doing it right. 

53:24
Dr. William Seeds
With GLP1s, it's inefficient muscle. It's muscle that your body is going to remove because it's not efficient. So the, again, the body's brilliant. It's going to remove that. It doesn't mean your strength's going to change it just means some muscle will go, but it has to go so that the overall goal is to improve more efficiency of more cells. And so you got to pay attention to that. You got to pay attention to hydration. There's all these things that go into doing something appropriately. And that's the problem that I believe is my thought out there that people are, they're healthcare providers that have the right intention. They just don't have enough information to, I think, to do it correctly. And that's what I. 

54:18
Dr. Larry Fan
And on that note, do you think that GLP1 like semaglutide, ozempic is actually more favorable compared to something like Tirzepatide UNTLP with gip? 

54:31
Dr. William Seeds
So I think so. That's a really good question. I think every generation. So Ozempic is a single peptide, a GLP one that's made by the L cell. Tirzepatide is two peptides, it's a GLP one and a gip, which is a glucagonic inhibitory peptide. And it's focused on making it a little more efficient in that weight loss pro in the cell's efficiency of utilizing fat, but also working on insulin sensitivity a little better around the body and glucose absorption. So it takes it a little step further. And then there's the next coming retatrutide, which is a triple agonist, three peptides, which is GLP1, GIP and glucagon. And that addition of glucagon does some things to add to the liver to be even better metabolically while you're going through this change to give you energy when it's needed. 

55:38
Dr. William Seeds
So and to it just you're mimicking more of the natural changes that happen. You know, we're getting smarter that okay, it isn't just one thing that happens. There's multiple communications that are happening. And so you're going to keep seeing iterations of this and it just gets better. So if you ask me, is tirzepatide is semaglutide a good peptide? I'd say absolutely. Is Tirzepatide better? Yes, it is. Is retatrutide this next peptide that will probably be FDA approved in 2025, is that better? Absolutely. Because they're getting more efficient in mimicking the normal communication of cells and it's just going to keep going that way. 

56:28
Dr. Larry Fan
And do you have any concerns maybe they work too well where it's causing people to lose weight too quickly and. 

56:33
Dr. William Seeds
That, you know, so in the wrong hands. Absolutely. Yeah. You have to respect that. And that's a. So does it with each iteration, does it. Do you have the potential of losing more weight? Yes, but you have to understand that and you have to really dial it back and utilize it correctly. 

56:57
Dr. Larry Fan
But at the same time saying, because there are additional peptides that are having additional physiologic improvements that you would, you know, that you believe that manure agents typically are better, but just they need to be used properly. 

57:11
Dr. William Seeds
Correct. And there's less side effects because you're becoming more efficient. And that's the game changer. And so you. It's. Yeah, I think it's just having that understanding that you have to be even more respectful of the up and coming better peptide. 

57:35
Dr. Larry Fan
Please join us next episode for part two of our interview with Dr. Seeds.